Functional ultrasound for high-resolution imaging of brain function and vasculature
We’re Iconeus –
A Paris-based company, founded by the inventors of functional ultrasound, who have developed an easy-to-use functional ultrasound system for imaging cerebral blood flow and microvasculature.
Its unique combination of sensitivity, speed and high resolution has enabled it to lead the field in preclinical studies on anesthetized or awake animals, and it is now being proposed for applications in clinical research too.
Iconeus One: Plug-and-play functional ultrasound imaging
Iconeus One is a breakthrough in brain research, offering through the same revolutionary technology both high-end neuroimaging and outstanding hemodynamic mapping. As well as allowing brain activity in mice, rats and other small animals to be imaged quickly and easily, it is now starting to be used for clinical research in humans too.
How does fUS neuroimaging work?
Functional ultrasound uses
plane-wave ultrasound
to generate 2D
images of blood flows across the brain in a matter of seconds. This makes it possible to follow changes in neuronal activation over time (thanks to the neurovascular coupling), or to generate 3D images of the entire brain vasculature.
As well as allowing mobile animals to be imaged using our compact probes, functional ultrasound provides far greater spatial and temporal coverage than the restricted ‘snapshots’ possible with conventional ultrasound. It’s also inherently sensitive, allowing it to spot small changes in neuronal activation much more readily than fMRI.
About us
We’ve assembled a talented team here at our facilities in Paris: experts in neuroscience, ultrasound physics and software engineering work side-by-side to develop new product features, and to fine-tune the technology for emerging applications.
Today, we’re as committed as ever to helping neuroscientists uncover new insights into brain function and diseases using the remarkable capabilities of functional ultrasound. Even in the short time since the technology became available, researchers have shed light on everything from basic brain functions to neuropsychiatric pathologies and possible treatments.
Applications of fUS brain imaging
Functional ultrasound has many applications in neuroscience, including in fundamental brain research, drug development, and investigations into neurodegenerative disorders and stroke. Across all of these areas, there are five main ways in which fUS can be used:
News & Events
Have a question about fUS imaging?
You are interested or intrigued by our technology and would like to discuss it?
Whatever you’d like to talk about – from the finer points of determining resting-state functional connectivity to the approximate price for a tailored Iconeus One system – there’s bound to be someone who can help (and they’re probably sitting next to us!).
So don’t hesitate to contact us!